In the first peer-reviewed, published study to evaluate the effects of the nutritional supplement methylsulfonylmethane (MSM) in horses, Spanish researchers found that MSM exerted a protective effect against the detrimental physiologic changes that occur during exercise. The study, “The effect of methyl sulphonyl methane supplementation on biomarkers of oxidative stress in sport horses following jumping exercise,” was published in the Nov. 7, 2008, edition of the journal Acta Veterinaria Scandinavica.
“During exercise, free radicals such as nitric oxide and carbon monoxide are generated that are highly damaging to organs, cells, and DNA,” explained Elena Vara, PhD, a member of the research team and professor of Biochemistry, from the Faculty of Medicine at Complutense University of Madrid. “In contrast, MSM is known to possess potent antioxidant properties that could potentially interfere with the production of these harmful free radicals.”
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